Key result
This review highlights recent developments in the physiology and pharmacology of key cardiac ion channels for therapeutic development and elucidates mechanisms for drug-induced cardiac side effects.
Design
Review
Authors
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May guide ion channel-targeted drug development with off-target cautions; leaves open clinical validation in prospective trials.
This review highlights recent developments in the physiology and pharmacology of cardiac ion channels for therapeutic development and understanding drug-induced side effects.
Priest et al. (2015) conducted a review in Cardiac pathophysiologies (e.g., atrial fibrillation, angina). Cardiac ion channels was evaluated. This review highlights recent developments in the physiology and pharmacology of key cardiac ion channels for therapeutic development and elucidates mechanisms for drug-induced cardiac side effects.
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