Key result
Low serum total cholesterol was independently associated with depression in elderly Finnish men (OR 0.67; 95% CI 0.48-0.94; p=0.022).
Why the study?
Are low serum total and LDL cholesterol levels associated with depressive symptoms in elderly men?
Population
421 elderly Finnish men aged 70 to 89 years from the 30-year follow-up of the Seven Countries Study
Comparison
Low serum total cholesterol and low LDL… vs Higher serum cholesterol levels
Design
Cohort
Authors
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Hypothesis-generating for depression risk in elderly men; should not yet change lipid management.
Cohort (n=421)
Yes
Are low serum total and LDL cholesterol levels associated with depressive symptoms in elderly men?
Odds Ratio: 0.67 (95% CI 0.48–0.94)
p-value: p=0.022
Low total and LDL cholesterol levels are independently associated with a higher prevalence of depressive symptoms in elderly men.
Äijänseppä et al. (2002) conducted a cohort in Depression (n=421). Low serum total cholesterol was evaluated on Depression (Zung sum score ≥ 48) (OR 0.67, 95% CI 0.48-0.94, p=0.022). Low serum total cholesterol was independently associated with depression in elderly Finnish men (OR 0.67; 95% CI 0.48-0.94; p=0.022).
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