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Investigates lean body mass metrics predicting pathologic findings in overweight endometrial cancer, suggesting advanced risk assessment methods.
Objectives: F-FDG PET/CT) parameters [lean body mass-corrected standardized uptake value (SUL)-based metrics] are superior to conventional SUV-based parameters for predicting adverse histopathologic features in overweight patients with endometrial cancer, and to explore their association with progression-free survival (PFS). Methods: F-FDG PET/CT followed by primary surgery were included. SUV- and SUL-based metabolic parameters were compared with histopathologic risk factors. ROC analyses were performed to determine discriminatory performance and optimal cut-off values. PFS was assessed using Kaplan-Meier analysis. Results: cut-off (log-rank p=0.46). Although SUL-based parameters may contribute to preoperative risk assessment, their prognostic value for survival remains uncertain.
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Avcı et al. (2026) studied this question.
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