Choroidal Neovascular Membrane Secondary to Optic Disk Drusen and Peripapillary Ovoid Hyperreflective Mass-like Structures: A Case Report

Summary Choroidal neovascular membrane (CNVM) is a rare but vision-threatening complication of optic disk drusen (ODD), particularly uncommon in pediatric patients. We report a case of a 13-year-old female who presented with acute visual deterioration in the left eye and was found to have peripapillary CNVM associated with buried ODD and peripapillary ovoid hyperreflective mass-like structures (PHOMS), where multimodal imaging was critical in establishing the diagnosis. Treatment with intravitreal aflibercept resulted in anatomical regression of the neovascular membrane and functional visual improvement. This case highlights the importance of recognizing PHOMS and ODD as potential risk factors for CNVM and underscores the role of optical coherence tomography-A in diagnosis and monitoring.