Retrospective cohort analysis shows weight loss maintenance in patients with structured programs over two years, highlighting predictors.
Key Points
This study aims to evaluate the maintenance of early weight loss in a structured obesity-care program over one and two years, examining differences by sex and diabetes status.
Conducted a retrospective cohort analysis of patients in a structured weight-management clinic.
Assessed weight changes at baseline, 3 months, 12 months, and 24 months after intervention.
Used multivariable logistic regression to identify predictors of maintenance, including early percent loss and demographics.
At 12 months, 86.0% (202 of 235) maintained ≥70% of initial loss; at 24 months, 72.3% (94 of 130) maintained ≥50%.
Maintainers achieved a mean weight reduction of 11.3 kg at 24 months compared to 1.1 kg in non-maintainers.
Greater early weight loss was a strong predictor of long-term maintenance with an adjusted odds ratio of 1.18 (95% CI, 1.03-1.35).