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July 28, 2026MedicinaOpen Access

Association Between Early Weight Loss and One-Year Weight Regain After Lifestyle-Based Obesity Treatment: A Retrospective Cohort Study

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Authors

İDİbrahim DoğanSDSerpil Sevimli DenizMBMehmet Kadir Bartın

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Overview

Retrospective cohort study examines early weight loss impact on weight regain in adults, indicating significant implications for obesity management.

Key Points

  • This study aims to investigate the relationship between early weight loss and one-year weight regain in individuals undergoing obesity treatment.
  • Retrospective cohort study of adults in a lifestyle-based obesity management program at a tertiary care clinic.
  • Early weight loss defined as percentage reduction in body weight from baseline to three months.
  • Logistic regression analysis adjusted for age, baseline body mass index, and baseline body weight.
  • Among 79 participants, 9 (11.4%) experienced clinically significant weight regain at one year.
  • Early weight loss was linked to lower odds of weight regain (adjusted odds ratio 0.784, 95% CI 0.646–0.950; p = 0.013).
  • Associations were consistent in sensitivity analyses, except the alternative weight regain definition did not reach significance.

Cite This Study

Doğan et al. (2026) studied this question.

synapsesocial.com/papers/6a6851062845b684d16f04cahttps://doi.org/10.3390/medicina62081450
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Also Consider

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