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January 1, 2026The AnalystOpen Access

IrTMes – a stable SABRE catalyst for the hyperpolarization of [1- ¹³ C]-pyruvate

Jakoba Wacker Jan G. Korvink Sören Lehmkuhl

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Key Points

This research aims to develop a stable catalyst for enhancing the hyperpolarization of [1-13C]-pyruvate.
Utilized IrTMes as a polarization transfer catalyst.
Conducted experiments at room temperature to assess stability and efficiency.
Achieved significant hyperpolarization of [1-13C]-pyruvate using IrTMes.
Demonstrated stability of the catalyst over time.

Implication

Demonstrates effective hyperpolarization of [1-13C]-pyruvate using IrTMes catalyst, implying potential advancements in imaging.

Abstract

A stable polarization transfer catalyst IrTMes for the SABRE hyperpolarization of [1- 13 C]-pyruvate at room temperature.

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Cite This Study

Wacker et al. (2026) studied this question.

synapsesocial.com/papers/6a250be87def13d035e1be2c https://doi.org/10.1039/d6an00328a

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