What does this research mean for the field?

For 2–3 cm renal stones, flexible vacuum-assisted ureteral access sheath-assisted flexible ureteroscopic lithotripsy (FV-UAS-assisted fURL) achieves stone-free rates comparable to mini-percutaneous nephrolithotomy (mPCNL) while reducing hemoglobin loss, postoperative pain, and hospital stay, and improves upon conventional fURL in operative time and costs. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to compare the efficacy and safety of FV-UAS-assisted fURL, UAS-assisted fURL, and mPCNL in managing 2–3 cm renal stones.

June 7, 2026Therapeutic Advances in UrologyOpen Access

Comparison of the efficacy and safety of flexible vacuum-assisted ureteral access sheath–assisted flexible ureteroscopic lithotripsy, conventional ureteral access sheath–assisted flexible ureteroscopic lithotripsy, and mini-percutaneous nephrolithotomy for 2–3 cm renal stones

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Authors

HGHao GuNorthwest University SXSong XueNorthwest University YLYonghua LeiNorthwest University

Discussion

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Implication

Retrospective comparative study comparing FV-UAS-assisted fURL, UAS-assisted fURL, and mPCNL outcomes for renal stone treatment, indicating safer options with less morbidity.

Key Points

This study aims to compare the efficacy and safety of FV-UAS-assisted fURL, UAS-assisted fURL, and mPCNL in managing 2–3 cm renal stones.
Retrospective single-center comparative study involving 156 patients with 2–3 cm renal stones.
Patients were divided into FV-UAS group (n=50), UAS group (n=54), and mPCNL group (n=52) and evaluated for perioperative outcomes.
Outcomes measured included operative time, hemoglobin decrease, postoperative pain, hospital stay, costs, and stone-free rates.
Operative time was shortest in the FV-UAS group (77.56 min) compared to UAS (85.04 min) and mPCNL (67.60 min), p < 0.05.
Hemoglobin decrease was lower in FV-UAS (3.50 g/L) and UAS (4.01 g/L) than mPCNL (13.86 g/L), p < 0.001.
Stone-free rates at 1 month were 96.0% for FV-UAS and 96.2% for mPCNL, both higher than UAS (81.5%), p < 0.05.

Cite This Study

Gu et al. (2026) studied this question.

synapsesocial.com/papers/6a250c957def13d035e1cb5f https://doi.org/10.1177/17562872261452324

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Implication

Retrospective comparative study comparing FV-UAS-assisted fURL, UAS-assisted fURL, and mPCNL outcomes for renal stone treatment, indicating safer options with less morbidity.

Comparison of the efficacy and safety of flexible vacuum-assisted ureteral access sheath–assisted flexible ureteroscopic lithotripsy, conventional ureteral access sheath–assisted flexible ureteroscopic lithotripsy, and mini-percutaneous nephrolithotomy for 2–3 cm renal stones

Discussion

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Key Points

Cite This Study

Comparison of the efficacy and safety of flexible vacuum-assisted ureteral access sheath–assisted flexible ureteroscopic lithotripsy, conventional ureteral access sheath–assisted flexible ureteroscopic lithotripsy, and mini-percutaneous nephrolithotomy for 2–3 cm renal stones

Discussion

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Implication

Key Points

Cite This Study

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