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June 7, 2026Diabetes

Healthy diets are associated with ~175% higher odds of meeting HbA1c, BP, and LDL-C targets.

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Why the study?

Dietary patterns exhibit regional characteristics and are linked to metabolic status, but the relationship between specific dietary patterns and metabolic management in diabetic patients in Guangdong Province required investigation.

Does a healthy dietary pattern improve metabolic control (HbA1c, blood pressure, and LDL-C) in adult diabetic patients?

Population

1,465 diabetic patients in Guangdong Province

Comparison

Higher vs lower adherence quartiles of identified dietary patterns

Design

Cross-sectional analysis

Key result

A healthy dietary pattern was associated with significantly higher odds of achieving combined HbA1c, blood pressure, and LDL-C targets compared to the lowest quartile (OR 2.745; 95% CI 1.356-5.561).

Authors

XCXUANRONG CHENZLZHIGU LIUW(Wei Jiang (14986)

Discussion

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Member takes

Overview

Should not yet change diabetes care; hypothesis-generating for dietary patterns improving combined targets.

Key Points

  • This study aims to investigate the connection between dietary patterns and metabolic management in adults with diabetes in Guangdong.
  • Data from the Chinese Diabetes Complications Study involving 1,465 patients were analyzed.
  • Dietary habits were assessed using a semi-quantitative food frequency questionnaire.
  • Principal component analysis identified dietary patterns; logistic regression analyzed associations with metabolic metrics.
  • Q3 participants had an OR of 1.650 (CI 1.280 - 2.126, p<0.001) for meeting HbA1c targets compared to Q1.
  • The OR for blood pressure targets in Q3 versus Q1 was 1.770 (CI 1.358 - 2.308, p<0.001).
  • The combined odds of meeting HbA1c, BP, and LDL-C targets was 2.745 (CI 1.356 - 5.561, p=0.005).

Study Design

Type

Cross-Sectional (n=1,465)

Structured PICO

Does a healthy dietary pattern improve metabolic control (HbA1c, blood pressure, and LDL-C) in adult diabetic patients?

P
Population
1,465 adult diabetic patients from the Guangdong section of the Chinese Diabetes Complications Study assessed for dietary patterns and metabolic control.
E
Exposure
Highest quartile (Q3) of a 'healthy dietary pattern' characterized by high intake of whole grains, tubers, fresh fruits, dairy, and poultry
C
Comparator
Lowest quartile (Q1) of the 'healthy dietary pattern'
O
Outcome
Meeting HbA1c, blood pressure, and LDL-C targetssurrogate

Main Result

Odds Ratio: 2.745 (95% CI 1.356–5.561)

p-value: p=0.005

A healthy dietary pattern is associated with significantly better achievement of blood glucose, blood pressure, and lipid targets in adult diabetic patients, independent of total caloric intake.

Cite This Study

CHEN et al. (2026) conducted a cross-sectional in Diabetes (n=1,465). Healthy dietary pattern vs. Lowest quartile (Q1) of healthy dietary pattern was evaluated on Combined achievement of HbA1c, blood pressure, and LDL-C targets (OR 2.745, 95% CI 1.356 - 5.561, p=0.005). A healthy dietary pattern was associated with significantly higher odds of achieving combined HbA1c, blood pressure, and LDL-C targets compared to the lowest quartile (OR 2.745; 95% CI 1.356-5.561).

synapsesocial.com/papers/6a250cbc7def13d035e1ce91https://doi.org/10.2337/db26-1530-p
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association between PCA-derived dietary pattern and metabolic control among adults with diabetes in Guangdong Province: a cross-sectional study2026
  2. 265-PUB: Relationship between Dietary and Metabolic Control in Patients with DM in Guangdong Province2024
  3. 3The prevalence of comorbidities and the metabolic control status in patients with diabetes mellitus in Guangdong Province of China: a cross-sectional study2026 · 1 citations
  4. 4Associations of nutrient intake, dietary behaviours, and patterns with metabolic profiles and obesity measures: findings from a cross-sectional study in a southern Chinese population2025 · 2 citations
  5. 5Trends in Glycemic and Cardiovascular Risks Control in Cantonese Adults in Primary Healthcare Settings: 2018 to 20222025