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June 30, 2025Diabetes Metabolic Syndrome and ObesityOpen Access

From 2018 to 2022, the standardized percentage of primary care patients with type 2 diabetes achieving control of fasting glucose, LDL, and BMI improved, while blood pressure and HDL control significantly decreased.

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Why the study?

Glycemic and cardiovascular risk control in patients with T2DM managed in primary healthcare settings remains challenging in urbanizing areas, prompting an analysis of 2018-2022 trends to identify care gaps.

Population

81,709 adults aged 30 years or older with T2DM across 24 primary healthcare settings in Baiyun district, Guangzhou

Comparison

Trends from 2018 to 2022

Design

Observational study analyzing real-world data

Key result

From 2018 to 2022, the standardized percentage of primary care patients with type 2 diabetes achieving control of fasting glucose, LDL, and BMI improved, while blood pressure and HDL control significantly decreased.

Authors

XWXueji WuXCXiongfei ChenXZXinghua Zhang

Discussion

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Overview

Persistent T2DM care gaps in Guangzhou PHC warrant targeted policy; leaves open optimal interventions and generalizability.

Study Design

Type

Observational (n=81,797)

Multicenter

Yes

Structured PICO

P
Population
81,797 adults aged 30 years or older with type 2 diabetes managed in primary healthcare settings in Guangzhou, China, evaluated for metabolic control trends from 2018 to 2022.
O
Outcome
Trends in the standardized percentage of participants with control of fasting blood glucose (FBG), blood pressure (BP), total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and BMI from 2018 to 2022.surrogate

Main Result

p-value: p=<0.05

While glycemic and lipid control improved among Cantonese adults with T2DM in primary care from 2018 to 2022, blood pressure and HDL control worsened, highlighting the need for targeted cardiovascular risk management in this high-risk population.

Limitations

  • Voluntary participation may over-represent health-conscious individuals while under-representing mobility-impaired elderly.
  • The primary outcome for diabetes control was fasting glucose rather than HbA1c, which may have led to an underestimation of poor glycemic control.
  • Information on the use of glucose-lowering, BP-lowering, and blood lipid-lowering medications was unavailable.

Cite This Study

Wu et al. (2025) conducted an observational in Type 2 diabetes mellitus (n=81,797). Time period (2018-2022) vs. 2018 (baseline) was evaluated on Trends in the standardized percentage of participants achieving clinical targets (fasting glucose, blood pressure, lipids, BMI) (p=<0.05). From 2018 to 2022, the standardized percentage of primary care patients with type 2 diabetes achieving control of fasting glucose, LDL, and BMI improved, while blood pressure and HDL control significantly decreased.

synapsesocial.com/papers/6a89845f1fb56efa37d4555bhttps://doi.org/10.2147/dmso.s519612
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The prevalence of comorbidities and the metabolic control status in patients with diabetes mellitus in Guangdong Province of China: a cross-sectional study2026 · 1 citations
  2. 2Lipid control in adult Chinese patients with type 2 diabetes: a retrospective analysis of time trends and geographic regional differences2021 · 4 citations
  3. 3Diabetes Mellitus and Hyperlipidemia Status Among Hypertensive Patients in the Community and Influencing Factors Analysis of Blood Pressure Control2025 · 12 citations
  4. 41530-P: The Relationship between Dietary Patterns and Metabolic Control among Adult Diabetic Patients in Guangdong Province2026
  5. 565-PUB: Relationship between Dietary and Metabolic Control in Patients with DM in Guangdong Province2024