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June 7, 2026Diabetes

Higher perceived risk is associated with ~36-fold greater odds of adequate ADRD knowledge in T2D.

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Why the study?

Despite evidence that midlife cardiovascular risk factors increase later-life cognitive decline, limited data exist on Alzheimer disease and related dementias knowledge and misconceptions among middle-aged adults with type 2 diabetes.

Population

102 adults with T2D (≥40 years)

Design

Cross-sectional study

Key result

Among adults with type 2 diabetes, 44% demonstrated adequate knowledge of ADRD, with higher perceived risk strongly associated with adequate knowledge (OR 35.56, p<0.001).

Authors

EOEYITAYO O. OWOLABIMBMICHELLE BOAKYERSRyan Seltzer

Discussion

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Member takes

Overview

Supports targeted ADRD education in T2D; leaves open whether perceived risk interventions improve knowledge or outcomes.

Key Points

  • This research aims to evaluate the knowledge of Alzheimer’s disease and related dementia among adults with type 2 diabetes and identify factors influencing this knowledge.
  • Conducted a cross-sectional study with 102 participants aged 40 and older.
  • Collected data on sociodemographic and clinical characteristics, and various measures of knowledge and social factors.
  • Applied multivariable logistic regression to identify associations with knowledge levels.
  • 44% of participants demonstrated adequate knowledge of Alzheimer’s disease.
  • Higher social support (OR=1.06, p=0.040), engagement in health-promoting behaviors (OR=1.17, p=0.017), and higher perceived risk (OR=35.56, p<0.001) were associated with better knowledge.
  • Social isolation (OR=0.07, p=0.019) and family history of dementia (OR=0.15, p=0.019) correlated with poorer knowledge, while higher education levels related to lower odds.

Study Design

Type

Cross-Sectional (n=102)

Structured PICO

P
Population
102 adults aged ≥40 years with type 2 diabetes assessed for knowledge of Alzheimer's disease and related dementias.
O
Outcome
ADRD knowledge and associated social and self-regulatory factorspatient reported

Main Result

Odds Ratio: 35.56

p-value: p=<0.001

Adults with T2D have limited knowledge of Alzheimer's disease and related dementias, highlighting the need for socially informed interventions to improve brain health literacy.

Cite This Study

OWOLABI et al. (2026) conducted a cross-sectional in Type 2 diabetes (n=102). Social and self-regulatory factors (e.g., perceived risk, social support) was evaluated on Adequate knowledge of ADRD (≥70% correct score) (OR 35.56, p=<0.001). Among adults with type 2 diabetes, 44% demonstrated adequate knowledge of ADRD, with higher perceived risk strongly associated with adequate knowledge (OR 35.56, p<0.001).

synapsesocial.com/papers/6a250cd27def13d035e1cfcdhttps://doi.org/10.2337/db26-1508-p
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 11253-P: Differential Risk of Dementia in Older Adults with Diabetes by Race/Ethnicity, Gender, and Age—Health and Retirement Study 1992–20202024
  2. 21252-P: Markers of Alzheimer's Disease (AD) in Young Adults with Type 1 Diabetes, With and Without Diabetic Retinopathy (DR)2024
  3. 3Abstract MP20: Incident Dementia Attributable to Diabetes in Midlife and Late-Life: The Atherosclerosis Risk in Communities Study2024
  4. 42362-P: Prediabetes and Cognitive Impairment: The Influence of Social Risk Factors, HRS 2006–20162026
  5. 5Determination of Alzheimer’s Disease-Related Knowledge and Stigma Levels of Adult Individuals2024