Why the study?
Does female gender affect the risk of long-term complications (reoperation, stroke, and death) in patients undergoing aortic or mitral valve replacement compared to male gender?
Population
3118 patients who underwent aortic valve replacement or mitral valve replacement between 1976 and 2006.
Comparison
Female gender vs Male gender
Design
Cohort
Follow-up
mean 5.6 (4.5) years
Authors
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May inform sex-specific AVR prosthesis choice; leaves open need for randomized confirmation of survival differences.
Does female gender affect the risk of long-term complications (reoperation, stroke, and death) in patients undergoing aortic or mitral valve replacement compared to male gender?
Women undergoing valve replacement surgery experience better overall long-term survival and fewer reoperations than men, despite a higher risk of late stroke with mechanical aortic prostheses.
Kulik et al. (2008) studied this question.
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