Population
Sheep coronary occlusion infarct model
Design
Preclinical
Follow-up
30 days
Authors
Loading...
No immediate clinical implications post-MI; leaves open whether targeting fibroblast connexins modifies remodeling.
Post-infarction tissue remodeling involves temporally and spatially distinct infiltration of fibroblasts expressing Cx45 and Cx43, which may mediate progressive infarction.
Patrizia Camelliti (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: