Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 7, 2026Transplant InternationalOpen Access

Present and future of liver transplantation for cholangiocellular carcinoma: moving toward personalized multiparametric transplantability patterns

View Full Paper
Ask AI
Bookmark
Share

Authors

UCUmberto CilloUniversity of PaduaAFAlessandro FurlanettoUniversity of PaduaJLJacopo LanariUniversity of Padua

Discussion

Loading...

Member takes

Implication

Randomized trial explores personalized transplantability in cholangiocarcinoma, suggesting refined selection enhances outcomes.

Key Points

  • The research aims to assess the evolving role of liver transplantation in cholangiocarcinoma and to propose personalized selection criteria.
  • Analyzed long-term outcomes of liver transplantation for cholangiocarcinoma patients under standardized protocols.
  • Investigated the integration of clinical, functional, histopathologic, molecular, and radiologic parameters for candidate selection.
  • Focused on identifying patients with indolent disease behavior for optimal graft utilization.
  • Liver transplantation for cholangiocarcinoma now shows long-term outcomes comparable to other oncologic indications.
  • Refined selection criteria and neoadjuvant therapies lead to improved results, particularly for perihilar and favorable tumor biology cases.
  • Future efforts will focus on multiparametric biological selection to optimize patient outcomes and resource use.

Cite This Study

Cillo et al. (2026) studied this question.

synapsesocial.com/papers/6a260fef1dde323095d3f104https://doi.org/10.3389/ti.2026.15786
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vascular Complications After Orthotopic Liver Transplantation After Neoadjuvant Therapy for Hilar Cholangiocarcinoma2007 · 115 citations
  2. 2Preoperative assessment of longitudinal extent in hilar cholangiocarcinoma using noninvasive enhanced MR radiomics: a multicenter study2025
  3. 3The Rationale for Combining Normothermic Liver Machine Perfusion with Continuous Renal Replacement Therapy to Maintain Physiological Perfusate during Ex Vivo Organ Perfusion2024 · 4 citations
  4. 4Radiomics of hepatopancreatobiliary cancer diagnosis, management, and future prospects2025 · 2 citations
  5. 5Defining Benchmarks in Liver Transplantation2017 · 257 citations