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March 7, 2026Journal of Liver CancerOpen Access

Contemporary overview of liver transplantation for intrahepatic cholangiocarcinoma and combined hepatocellular-cholangiocarcinoma

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Authors

HLHae Won LeeSeoul National University Bundang Hospital

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Overview

Narrative review analyzes emerging data on liver transplantation outcomes in specific cancer subgroups, indicating a clinical shift.

Key Points

  • The central aim is to explore evolving practices regarding liver transplantation for iCCA and cHCC-CCA.
  • Review of multicenter retrospective studies
  • Analysis of updated clinical practice guidelines
  • Synthesis of data on patient selection for liver transplantation
  • Identified a subgroup with 'very early' iCCA achieving excellent post-transplant outcomes
  • Guidelines updated to cautiously allow liver transplantation for selected iCCA patients
  • cHCC-CCA remains a significant challenge in diagnosis and treatment.

Cite This Study

Hae Won Lee (2026) studied this question.

synapsesocial.com/papers/69abc0b85af8044f7a4e972ehttps://doi.org/10.17998/jlc.2026.03.03
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Liver Transplantation for Cholangiocarcinoma2024 · 1 citations
  2. 2Present and future of liver transplantation for cholangiocellular carcinoma: moving toward personalized multiparametric transplantability patterns2026
  3. 3Advances in liver transplant oncology: Biology-driven selection, systemic therapy integration, and future trial frameworks2026
  4. 4The role of living donor liver transplantation in treating intrahepatic cholangiocarcinoma2024 · 7 citations
  5. 5Review Article: Liver Transplantation for Hepatocellular Carcinoma in the Era of Immune Checkpoint Inhibitors2025 · 1 citations