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This review aims to summarize current evidence on cognitive impairment in patients with glioma, focusing on mechanisms, assessment methods, and therapeutic strategies.

June 9, 2026CancersOpen Access

Cognitive Impairment in Patients with Glioma: Mechanisms, Assessment, and Emerging Therapeutic Strategies

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This review aims to summarize current evidence on cognitive impairment in patients with glioma, focusing on mechanisms, assessment methods, and therapeutic strategies.
Reviewed literature published from January 2000 to February 2026 on cognitive impairment in glioma.
Conducted structured searches in PubMed, Cochrane Library, and Google Scholar.
Identified studies discussing mechanisms, assessment, and management of cognitive deficits in glioma patients.
Cognitive deficits are common in glioma patients, influenced by tumor infiltration and treatment toxicity.
Modern radiotherapy techniques and IDH-targeted therapies like vorasidenib may delay cognitive decline.
Supportive pharmacotherapy and individualized neuropsychological rehabilitation show potential benefits for quality of life.

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Review summarizes cognitive impairment mechanisms and treatments in glioma patients, emphasizing assessment tools and therapies.

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Piec et al. (2026) studied this question.

synapsesocial.com/papers/6a27ae3fa963992e162684dd https://doi.org/10.3390/cancers18121865

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Cognitive Impairment in Patients with Glioma: Mechanisms, Assessment, and Emerging Therapeutic Strategies

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Cognitive Impairment in Patients with Glioma: Mechanisms, Assessment, and Emerging Therapeutic Strategies

Key Points

Discussion

Implication

Cite This Study

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