Key result
Dobutamine stress echocardiography for detecting coronary artery disease in patients with diabetes mellitus demonstrated a sensitivity of 82%, specificity of 54%, PPV of 84%, and NPV of 50%.
Why the study?
Does dobutamine stress echocardiography accurately detect coronary artery disease in patients with diabetes mellitus?
Population
52 patients with diabetes mellitus referred for cardiac assessment, mean age 59 years
Comparison
Dobutamine stress echocardiography (DSE) vs Coronary angiography as reference standard
Design
Cohort
Authors
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Low specificity limits DSE reliability for CAD detection in diabetes; leaves open need for validation against other modalities.
Observational (n=52)
Does dobutamine stress echocardiography accurately detect coronary artery disease in patients with diabetes mellitus?
Dobutamine stress echocardiography has low specificity (54%) for detecting significant coronary artery disease in patients with diabetes mellitus.
Hennessy et al. (1997) conducted an observational in Diabetes mellitus and suspected coronary artery disease (n=52). Dobutamine stress echocardiography vs. Coronary angiography was evaluated on Detection of significant CAD (> 50% luminal diameter stenosis on coronary angiography). Dobutamine stress echocardiography for detecting coronary artery disease in patients with diabetes mellitus demonstrated a sensitivity of 82%, specificity of 54%, PPV of 84%, and NPV of 50%.
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