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December 1, 1995Australian and New Zealand Journal of Medicine

Assessment of coronary artery disease by dobutamine stress echocardiography (DSE)

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Why the study?

Does dobutamine stress echocardiography accurately detect coronary artery disease and predict post-infarction cardiac events?

Population

137 consecutive patients referred for dobutamine stress echocardiography with suspected or documented…

Comparison

Dobutamine stress echocardiography (DSE) vs Coronary angiography

Design

Cohort

Follow-up

6 months (for post-infarction subgroup)

Authors

RCRobert ChanAustin HealthAndrew TonkinAndrew TonkinGeneral / Preventive / LipidsSBS. ByrgiotisHeidelberg Repatriation Hospital

Discussion

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Implication

DSE may aid post-MI CAD detection and risk stratification; leaves open need for randomized outcome trials before routine adoption.

Structured PICO

Does dobutamine stress echocardiography accurately detect coronary artery disease and predict post-infarction cardiac events?

P
Population
137 consecutive patients referred for dobutamine stress echocardiography (DSE) with suspected or documented coronary artery disease. Subgroups included 84 patients who also underwent coronary angiography and 35 patients who underwent DSE after uncomplicated myocardial infarction.
I
Intervention
Dobutamine stress echocardiography (DSE)
C
Comparator
Coronary angiography (as reference standard for diagnostic accuracy in 84 patients)
O
Outcome
Sensitivity and specificity for detecting and localising significant coronary artery disease, and predictive values for cardiac events following myocardial infarctionsurrogate

Dobutamine stress echocardiography is a safe, feasible, and accurate non-invasive imaging modality for detecting coronary artery disease and providing prognostic information after myocardial infarction.

Cite This Study

Chan et al. (1995) studied this question.

synapsesocial.com/papers/6a95cbcd54f829098c514303https://doi.org/10.1111/j.1445-5994.1995.tb02858.x

Topics

Echocardiography
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Complementary Value of Two-Dimensional Exercise Echocardiography to Routine Treadmill Exercise Testing1986 · 228 citations
  2. 2Low-dose dobutamine echocardiography detects reversible dysfunction after thrombolytic therapy of acute myocardial infarction.1993 · 403 citations
  3. 3Dobutamine: Ten Years Later1989 · 55 citations