Longitudinal evaluation from birth to adolescence of soy-protein based infant formula compared to cow’s-milk based formula and breastfeeding: A comprehensive summary of findings
Longitudinal trial examines health impacts of infant feeding types from birth to adolescence, indicating benefits of breastfeeding.
Key Points
This research investigates the long-term effects of soy-based and cow's milk-based infant formulas compared to breastfeeding on various health outcomes from infancy to adolescence.
Participants included 600 infants fed soy-based, cow's milk-based formulas, or breast milk; 200 per group.
Follow-up assessments were conducted at 6 and 14 years of age.
Outcomes measured include growth, body composition, cardiovascular health, gut microbiome, neurodevelopment, and reproductive maturation.
Breastfeeding led to slower weight gain and lower body mass index extending into adolescence compared to formula feeding.
Skeletal mineralization and most neurocognitive outcomes were similar across all feeding groups.
Distinct differences in cardiovascular autonomic measures and gut microbiome signatures were observed based on feeding mode.