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June 28, 2026Breastfeeding Medicine

Long-Term Weight Trajectories in Infants Receiving Prolonged Breastfeeding: Impact of Formula Supplementation

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Authors

RKRona Krinsky-DrorRLRonit LubetzkyDMDror Mandel

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Overview

Retrospective cohort study compares weight trajectories in infants based on breastfeeding and formula supplementation, suggesting physiological patterns.

Key Points

  • The aim is to compare weight trajectories in infants breastfed for at least 1 year, with or without formula supplementation.
  • Retrospective cohort of 252 infants followed in well-baby clinics
  • All infants breastfed for ≥12 months and received complementary foods at 4–6 months
  • Followed anthropometric data from birth to age 5.
  • Males breastfed without formula had a lower weight at 13-18 months (10.20 kg vs. 10.97 kg, p < 0.001)
  • No significant weight differences from 19 months onward, with convergence through 5 years
  • Differences in early weight may represent physiological patterns.

Cite This Study

Krinsky-Dror et al. (2026) studied this question.

synapsesocial.com/papers/6a40bae361bb0a67205c6ac5https://doi.org/10.1177/15568253261461838
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Associations Between Prolonged Breast-Feeding, Formula Supplementation, and Weight-for-Age Trajectories Through Five Years2025
  2. 2Effects of feeding patterns during the first 6 months on weight development of infants ages 0–12 months: a longitudinal study2024 · 9 citations
  3. 3Comparative analysis of the effects of early breastfeeding versus formula feeding on the growthand development of preterm infants2025
  4. 4Early Infant Feeding Practices and Associations with Growth in Childhood2024 · 10 citations
  5. 5Longitudinal evaluation from birth to adolescence of soy-protein based infant formula compared to cow’s-milk based formula and breastfeeding: A comprehensive summary of findings2026