Key result
Thrombus-in-transit across a PFO causes fatal sequential embolization to the LMCA and PA.
Why the study?
Paradoxical embolism via a PFO is a rare cause of acute myocardial infarction, and its simultaneous or sequential occurrence with pulmonary embolism is even rarer.
Population
A 60-year-old woman with no prior cardiac history presenting with anterior STEMI and cardiogenic shock
Design
Case report
Authors
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Urges immediate pulmonary evaluation if intracardiac thrombus vanishes in unstable PFO patients; case report leaves open optimal prevention strategies.
Case Report (n=1)
This case demonstrates that the sudden disappearance of an intracardiac thrombus in an unstable patient with a patent foramen ovale should prompt immediate evaluation for sequential pulmonary embolism.
Halder et al. (2026) conducted a case report in Paradoxical embolism via patent foramen ovale (n=1). Thrombus-in-transit across patent foramen ovale was evaluated on Sequential embolization to coronary and pulmonary circulations. Thrombus-in-transit across a patent foramen ovale caused rapid, sequential, and fatal embolization to both the left main coronary artery and pulmonary artery in a 60-year-old woman.
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