Why the study?
Application of fractional flow reserve in daily practice or research requires standardization to avoid technical or operator-related artifacts in pressure recordings.
This document proposes standardized methods for acquiring, recording, interpreting, and archiving fractional flow reserve measurements to reduce technical artifacts and enhance uniformity in clinical practice and research.
Captured external expert commentary on this paper, strongest first. Original sources are linked where available.
“Heterogeneity goes along with variability, and variability is one of the main reasons for imprecision. And the latter generates uncertainty and subjectivity, which is not affordable in clinical decisions.”
Adoption of these FFR standardization methods is warranted in clinical practice; extends prior consensus by providing detailed acquisition, recording, and archiving protocols.
Pressure wire–based fractional flow reserve is considered the standard of reference for evaluation of the ischemic potential of coronary stenoses and the expected benefit from revascularization. Accordingly, its application in daily practice or for research purposes has to be as standardized as possible to avoid technical or operator-related artifacts in pressure recordings. This document proposes a standardized way of acquiring, recording, interpreting, and archiving the pressure tracings for daily practice and for the purpose of clinical research involving a core laboratory. Proposed standardized steps enhance the uniformity of clinical practices and data interpretation.
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Tóth et al. (2016) conducted a review in Coronary stenoses. Standardized fractional flow reserve (FFR) measurements was evaluated. A standardized approach to acquiring, recording, interpreting, and archiving fractional flow reserve measurements is proposed to enhance the uniformity of clinical practices and data interpretation.
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