Why the study?
Does fractional flow reserve (FFR)-guided revascularization improve clinical outcomes compared to angiography-guided revascularization or medical therapy in patients with coronary artery disease?
Does fractional flow reserve (FFR)-guided revascularization improve clinical outcomes compared to angiography-guided revascularization or medical therapy in patients with coronary artery disease?
FFR is the gold standard for identifying ischemia-causing coronary stenoses, and FFR-guided revascularization improves clinical outcomes compared to angiography-guided PCI or medical therapy alone.
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May inform PCI decisions in CAD; leaves open need for new RCTs to confirm durability beyond 1 year.
Nico H.J. Pijls (2013) studied this question.
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