Key result
Fractional flow reserve remains the gold standard for detecting ischemia-inducing coronary stenoses, with FFR-guided PCI demonstrating superiority over angiography-guided PCI and medical therapy alone.
Why the study?
Does FFR-guided PCI improve outcomes compared to angiography-guided PCI or medical therapy alone in patients with coronary artery disease?
Population
Patients with coronary artery disease (CAD)
Comparison
Fractional flow reserve-guided percutaneous… vs Angiography-guided PCI or medical therapy alone
Design
Review
Authors
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Supports FFR use in ischemia assessment; leaves open need for updated RCTs in contemporary cohorts.
Does FFR-guided PCI improve outcomes compared to angiography-guided PCI or medical therapy alone in patients with coronary artery disease?
This review reinforces that FFR is the gold standard for identifying ischemia-inducing coronary stenoses and supports FFR-guided PCI over angiography-guided PCI or medical therapy alone.
Mangiacapra et al. (2018) conducted a review in Coronary artery disease (CAD). Fractional flow reserve (FFR) vs. Angiography alone and non-hyperemic indices was evaluated. Fractional flow reserve remains the gold standard for detecting ischemia-inducing coronary stenoses, with FFR-guided PCI demonstrating superiority over angiography-guided PCI and medical therapy alone.
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