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June 11, 2026Acute Medicine & SurgeryOpen Access

Feasibility of Early Enteral Nutrition in Patients Under Mechanical Circulatory Support

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Authors

CMChikai MitsuharaKSKentaro ShimizuTETakeshi Ebihara

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Overview

Retrospective study evaluates early enteral nutrition effects in ICU patients on mechanical support, indicating feasibility without complications.

Key Points

  • This study aims to assess the safety of early enteral nutrition for patients on mechanical circulatory support.
  • Retrospective observational study at a Japanese tertiary hospital.
  • Included adult patients supported with intra-aortic balloon pumping and/or veno-arterial ECMO in the ICU > 1 week.
  • Patients divided into early (within 48 hours) and late (after 48 hours) enteral nutrition groups.
  • Early group: 16 patients initiated enteral nutrition within 48 hours; late group: 39 patients after 48 hours.
  • Energy intake significantly increased in the early group between Day 2 and Day 5; no difference after Day 6.
  • No significant differences in gastrointestinal complications or mortality (35% early vs. 44% late).

Cite This Study

Mitsuhara et al. (2026) studied this question.

synapsesocial.com/papers/6a2a50e080c8f91e7f39d4d3https://doi.org/10.1002/ams2.70132
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of early versus late enteral nutrition on the nutritional status of surgical intensive care unit patients: A retrospective observational study.2025
  2. 2Effects of enteral nutrition initiation time and nutritional adequacy on the prognosis of critically ill adults: systematic review and meta-analysis2026
  3. 3Early enteral nutrition increases 28-day mortality in patients with sepsis who are on invasive mechanical ventilation: A retrospective analysis based on the MIMIC - IV database2024
  4. 4Effectiveness of Registered Dietitian-Led Management of Early Nutritional Support in the Emergency Intensive Care Unit: A Retrospective Observational Study2024
  5. 5Early Enteral Nutrition Provided Within 24 Hours of ICU Admission: A Meta-Analysis of Randomized Controlled Trials*2018 · 147 citations