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June 11, 2026Skin Health and DiseaseOpen Access

Narrowband ultraviolet B and psoralen plus ultraviolet A phototherapy treatment for mycosis fungoides: a 17-year retrospective cohort study in a university teaching hospital, 2007–24

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Authors

TBThandiwe BandaSandwell & West Birmingham Hospitals NHS TrustKAKashini AndrewBirmingham City HospitalDLDanning LiBirmingham City Hospital

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Overview

Retrospective cohort study evaluates NB-UVB and PUVA effectiveness in mycosis fungoides, indicating predictors of response.

Key Points

  • To evaluate and compare the outcomes of narrowband ultraviolet B (NB-UVB) and psoralen plus ultraviolet A (PUVA) in treating mycosis fungoides (MF).
  • Retrospective cohort study of 33 patients treated with NB-UVB or PUVA between 2007 and 2024.
  • Patients were biopsied and assessed for response to therapies.
  • Statistical analysis was performed using Microsoft Excel and R.
  • Complete remission achieved in 15 cases (45%), partial remission in 15 cases (45%), and no response in 3 cases (9%).
  • Hypopigmented MF had better outcomes (P=0.02) compared to hyperpigmented MF.
  • Advanced stage at treatment initiation was associated with poorer outcomes (P=0.009).

Cite This Study

Banda et al. (2026) studied this question.

synapsesocial.com/papers/6a2a510680c8f91e7f39d609https://doi.org/10.1093/skinhd/vzag039
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of narrowband ultraviolet B with psoralen plus ultraviolet A phototherapy for patients with early-stage mycosis fungoides: a systematic review and meta-analysis2026
  2. 2Effectiveness of narrowband ultraviolet B monotherapy versus combination therapy with systemic agents in patients with early‐stage mycosis fungoides and the association with plaque lesions2024
  3. 3Pediatric Hypopigmented Mycosis Fungoides: A Narrative Literature Review of Phototherapy Dosing Regimens2026
  4. 4Pediatric Papular Mycosis Fungoides Treated With Phototherapy: A Case Series2025
  5. 5Adult-Onset Hypopigmented Mycosis Fungoides: A Systematic Review of Clinicopathologic, Immunophenotypic, and Therapeutic Characteristics2026