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June 11, 2026Nefrología (English Edition)Open Access

Reversible podocytopathy in a patient with blastoid-variant mantle cell lymphoma: A case of paraneoplastic FSGS and a literature review

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Authors

CVCatarina VeigaIDines damasioJMJoaquim Milheiro

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Overview

Case report shows reversible kidney damage in a lymphoma patient, suggesting paraneoplastic effects.

Key Points

  • This case aims to highlight the rare association between mantle cell lymphoma and reversible focal segmental glomerulosclerosis.
  • Case report of a 69-year-old man with nephrotic syndrome and acute kidney injury.
  • Kidney biopsy confirmed focal segmental glomerulosclerosis.
  • Lymphoma-directed chemotherapy was administered, leading to symptom resolution.
  • Nephrotic syndrome resolved post-chemotherapy, indicating successful treatment.
  • Renal function significantly improved, supporting the hypothesis of a paraneoplastic mechanism.
  • Recognition of this condition can prevent unnecessary immunosuppression.

Cite This Study

Veiga et al. (2026) studied this question.

synapsesocial.com/papers/6a2a515980c8f91e7f39daadhttps://doi.org/10.1016/j.nefroe.2026.501512
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nephrotic Syndrome Secondary to Mantle Cell Lymphoma: A Case Report2026
  2. 2Focal Segmental Glomerulosclerosis Secondary to Hodgkin’s Lymphoma: A Case Report2024
  3. 3A102-02 Podocyte Under Pressure: Collapsing Lupus Podocytopathy Diagnosed When Kidney Biopsy Beat the Marrow Call2026
  4. 4Case Report: Membranous nephropathy associated with mantle cell lymphoma: a rare case2025
  5. 5Concurrent κ light chain proximal tubulopathy and crystal-storing histiocytosis in monoclonal gammopathy of renal significance: a rare case report with 4-year follow-up and literature review2026