Key result
Ischemic mitral regurgitation on arrival worsened 30-day prognosis (P=0.02), and persistent IMR in the chronic phase worsened long-term prognosis (P=0.04) after acute myocardial infarction.
Why the study?
Does the presence and course of ischemic mitral regurgitation affect short- and long-term prognosis in patients with acute myocardial infarction undergoing primary PCI?
Population
546 consecutive patients with first-onset acute myocardial infarction
Design
Cohort
Follow-up
6 to 8 months (late post-PCI) and long-term
Authors
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IMR on arrival and persistence may refine post-AMI risk stratification; leaves open whether targeted IMR therapy alters outcomes.
Cohort (n=546)
Does the presence and course of ischemic mitral regurgitation affect short- and long-term prognosis in patients with acute myocardial infarction undergoing primary PCI?
p-value: p=0.02 and 0.04
The presence of ischemic mitral regurgitation on arrival and its persistence in the chronic phase after primary PCI for acute myocardial infarction are associated with worse short- and long-term prognosis.
Nishino et al. (2016) conducted a cohort in Acute myocardial infarction (n=546). Ischemic mitral regurgitation vs. Absence or improvement of ischemic mitral regurgitation was evaluated on 30-day and long-term prognosis (p=0.02 and 0.04). Ischemic mitral regurgitation on arrival worsened 30-day prognosis (P=0.02), and persistent IMR in the chronic phase worsened long-term prognosis (P=0.04) after acute myocardial infarction.
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