Key result
Antihypertensive treatment significantly lowered the risk for recurrent stroke (RR 0.73; 95% CI 0.62-0.87; P<0.001) compared to placebo in patients with previous cerebrovascular events.
Why the study?
Does antihypertensive treatment reduce recurrent stroke and cardiovascular events in patients with previous cerebrovascular events?
Meta-Analysis
Does antihypertensive treatment reduce recurrent stroke and cardiovascular events in patients with previous cerebrovascular events?
Relative Risk: 0.73 (95% CI 0.62–0.87)
p-value: p=<0.001
The extent of blood pressure reduction is linearly associated with the magnitude of risk reduction in recurrent cerebrovascular and cardiovascular events, supporting strict BP control for secondary stroke prevention.
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Supports strict BP control in secondary stroke prevention; confirms linear association between greater BP reduction and lower recurrent event risk.
Katsanos et al. (2016) conducted a meta-analysis in Previous cerebrovascular events. Antihypertensive treatment vs. Placebo was evaluated on Recurrent stroke (RR 0.73, 95% CI 0.62-0.87, p=<0.001). Antihypertensive treatment significantly lowered the risk for recurrent stroke (RR 0.73; 95% CI 0.62-0.87; P<0.001) compared to placebo in patients with previous cerebrovascular events.
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