What question did this study set out to answer?

This research aims to evaluate the treatment effects of antipsychotic medications versus non-antipsychotic treatments on catatonia and psychosis symptoms in hospitalized patients.

June 12, 2026Psychopharmacology BulletinOpen Access

Catatonia Associated with Psychosis: A Retrospective Study of 164 Inpatients

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Authors

TMTimothy R MooreUniversity of Florida TATamara D AlmeydaUniversity of Florida ESEdward K SilbermanTufts Medical Center

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Implication

Retrospective study finds better improvement in symptoms with treatment without antipsychotics in inpatients.

Key Points

This research aims to evaluate the treatment effects of antipsychotic medications versus non-antipsychotic treatments on catatonia and psychosis symptoms in hospitalized patients.
Retrospective analysis of 164 patients diagnosed with catatonia from July 2018 to September 2023.
Participants were divided into two groups: Group A received antipsychotics with benzodiazepines/ECT; Group B received benzodiazepines/ECT without antipsychotics.
ANOVA was used to analyze comparison of symptom scores from admission to discharge.
The antipsychotic-treated group had significantly higher Bush Francis Catatonia Rating Scale scores at discharge (p < 0.0001).
Significantly higher scores on the positive symptom subscale of the Positive and Negative Syndrome Scale at discharge were observed in the antipsychotic-treated group (p < 0.0001).
Improvements were greater in the group receiving only benzodiazepines/ECT compared to those treated with antipsychotics.

Cite This Study

Moore et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba18c8101cf8926f00fb7 https://doi.org/10.64719/pb.18513

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Catatonia Associated with Psychosis: A Retrospective Study of 164 Inpatients

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Key Points

Cite This Study

Catatonia Associated with Psychosis: A Retrospective Study of 164 Inpatients

Discussion

Member takes

Implication

Key Points

Cite This Study

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