Key result
Transcatheter valve-in-valve lowers mean tricuspid gradient to 4 mmHg in a degenerated bioprosthesis case.
Why the study?
Transcatheter valve-in-valve implantation has emerged as a promising option for degenerated tricuspid bioprosthetic valves in high-risk patients.
Does transcatheter valve-in-valve implantation improve hemodynamics and symptoms in a patient with a degenerated bioprosthetic tricuspid valve?
Case Report (n=1)
No
Does transcatheter valve-in-valve implantation improve hemodynamics and symptoms in a patient with a degenerated bioprosthetic tricuspid valve?
Transcatheter valve-in-valve implantation using a Myval transcatheter heart valve is a feasible and effective alternative to high-risk redo surgery for degenerated tricuspid bioprostheses.
May support TVIV feasibility in high-risk tricuspid degeneration; leaves open need for larger prospective trials.
Transcatheter valve-in-valve (TVIV) implantation has emerged as a promising treatment option for patients with degenerated tricuspid bioprosthetic valves, especially for those who are considered highrisk for traditional surgical interventions. This report highlights the case of a patient who had previously undergone bioprosthetic valve replacement due to functional tricuspid regurgitation. After 10 years, the patient presented with valve degeneration and was successfully treated with a TVIV procedure using a 29 mm Myval transcatheter heart valve (Meril Life Sciences, Vapi, Gujarat, India). The outcome was favorable, demonstrating the potential of TVIV for managing bioprosthetic valve failure in such high-risk patients.
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Alsancak et al. (2025) conducted a case report in Degenerated bioprosthetic tricuspid valve (n=1). Transcatheter valve-in-valve (TVIV) implantation was evaluated on Mean tricuspid valve gradient. Transcatheter valve-in-valve implantation successfully reduced the mean tricuspid gradient from 22 mmHg to 4 mmHg in a high-risk patient with a degenerated bioprosthesis, with no rehospitalizations at 1 year.
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