Waldenström Macroglobulinemia Presenting With Hepatic Lesions: Case Report and Literature Review
Authors
Discussion
Loading...
Member takes
Implication
Case report describes hepatic lesions in a patient with Waldenström macroglobulinemia, suggesting diagnostic challenges.
Key Points
- To report a rare presentation of Waldenström macroglobulinemia with focal hepatic lesions and to emphasize the importance of accurate diagnosis.
- Described clinical history and laboratory findings of a 63-year-old woman with IgM secretion and hepatic lesions.
- Conducted imaging studies which revealed multiple hypodense hepatic lesions and performed liver biopsy for histopathological evaluation.
- Administered six treatment cycles of bendamustine and rituximab.
- Patient showed significant reduction in hepatic lesions and IgM levels following treatment with bendamustine and rituximab.
- Granulomatous inflammation with necrosis was revealed in liver biopsy, consistent with WM involvement.
- Treatment was complicated by persistent cytopenias during the therapy.
Cite This Study
Sternbach et al. (2026) studied this question.