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The aim is to identify the novel HLA-A*32:181 allele through specific genetic analysis.

June 12, 2026HLA

Identification of the Novel HLA‐A*32:181 Allele Using Polymerase Chain Reaction Sequence‐Based Typing

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The aim is to identify the novel HLA-A*32:181 allele through specific genetic analysis.
Utilized polymerase chain reaction for allele identification.
Performed sequence-based typing to confirm genetic differences.
Focused on a specific nucleotide substitution in exon 3.
HLA-A*32:181 was identified, differing from HLA-A*32:01:01:01 by one nucleotide substitution.
The substitution occurs at position 500 (C>T) in exon 3.

Novel allele identification using sequence-based typing, indicating a new genetic variant.

HLA-A*32:181 differs from HLA-A*32:01:01:01 by one single nucleotide substitution at position 500 C>T in exon 3.

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He et al. (2026) studied this question.

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Novel allele identification using sequence-based typing, indicating a new genetic variant.

HLA-A*32:181 differs from HLA-A*32:01:01:01 by one single nucleotide substitution at position 500 C>T in exon 3.