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June 1, 2026HLA

The Novel HLA‐C*08:317 Allele Identified by Next‐Generation Sequencing

Hui Liu Yiou Fan

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Key Points

This research aims to identify a new allele, HLA-C*08:317, and its differences from the known HLA-C*08:01:01:01 allele.
Utilized next-generation sequencing for allele identification.
Focused on substitution analysis to discern genetic variations.
HLA-C*08:317 was identified as differing from HLA-C*08:01:01:01 by a C>T substitution at cDNA position 422.

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Implication

Novel allele HLA-C*08:317 identified via next-generation sequencing, suggesting genetic diversity in HLA genes.

Abstract

HLA-C*08:317 differs from HLA-C*08:01:01:01 by a C>T substitution at cDNA position 422.

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba44e8101cf8926f02cc8 https://doi.org/10.1111/tan.70793

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Characterisation of the Novel <i>HLA‐C*08:01:37</i> Allele by Next‐Generation Sequencing2025 · 2 citations
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4Characterisation of the Novel <i>HLA‐C*07:01:124</i> Allele by Next‐Generation SequencingOriginal Research · 2026 · 1 citations
5Characterisation of the Novel <i>HLA‐C*07:1226</i> Allele by Next Generation SequencingOriginal Research · 2026 · 1 citations

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