Key result
Modified UNICORN anchoring enables leaflet laceration and valve implantation in a failing sutureless bioprosthesis.
Why the study?
Sutureless bioprostheses present unique challenges for valve-in-valve transcatheter aortic valve implantation due to their frame architecture and proximity to coronary ostia.
Case Report (n=1)
The modified UNICORN guide anchoring technique provides a viable method for securing ventricular access and enabling mechanical leaflet laceration during valve-in-valve TAVI in patients with high-risk coronary anatomy.
May facilitate valve-in-valve TAVI in high-risk anatomy; leaves open need for prospective trials before wider adoption.
BACKGROUND: Sutureless bioprostheses present unique challenges for valve-in-valve (ViV) transcatheter aortic valve implantation due to their frame architecture and proximity to coronary ostia. CASE SUMMARY: A 71-year-old woman with a failing Perceval valve with high-risk coronary anatomy precluding chimney stenting and Bioprosthetic Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction. Leaflet traversal of the right coronary cusp was achieved through an MPA1 guide. The guide was advanced across the bioprosthetic frame into the left ventricle immediately post-traversal to secure position. This facilitated wire exchange and leaflet laceration. A balloon-expandable valve was then successfully implanted. DISCUSSION: Unlike stented valves, the sutureless valve crown creates a mechanical trap. Its 1-mm clearance precluded chimney stenting due to sandwich compression risk, whereas effaced sinuses prevented Bioprosthetic Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction leaflet splaying. The modified UNICORN guide anchoring maneuver bypassed these hurdles, securing the ventricle to facilitate stable, efficient mechanical modification in no-option anatomy. TAKE-HOME MESSAGE: Guide anchoring provides a shorter blueprint for complex scenarios by securing ventricular access and enabling mechanical laceration.
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Althobaiti et al. (2026) conducted a case report in Failing Perceval valve with high-risk coronary anatomy (n=1). Modified UNICORN guide anchoring maneuver was evaluated on Successful implantation of a balloon-expandable valve. The modified UNICORN guide anchoring maneuver successfully facilitated leaflet laceration and balloon-expandable valve implantation in a patient with a failing sutureless bioprosthesis.
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