Key result
More than 14 systolic arterial pressure reductions during the first 15 minutes of tilt predicted a positive tilt test with 80% sensitivity and 85% specificity in a prospective validation cohort.
Why the study?
Does the evaluation of systolic arterial pressure reductions during the first 15 minutes of a tilt table test predict a positive tilt outcome in healthy subjects with unexplained syncope?
Population
318 consecutive healthy subjects with unexplained syncope
Comparison
Evaluation of beat-to-beat systolic arterial… vs Subjects with a negative tilt test result
Design
Cohort
Authors
Loading...
May shorten tilt protocols in unexplained syncope; hypothesis-generating pending randomized validation.
Observational (n=318)
Does the evaluation of systolic arterial pressure reductions during the first 15 minutes of a tilt table test predict a positive tilt outcome in healthy subjects with unexplained syncope?
Absolute Event Rate: 328% vs 119%
p-value: p=<0.01
Evaluating systolic arterial pressure reductions during the first 15 minutes of a tilt test can accurately predict tilt-induced syncope, potentially allowing for a shortened test duration.
Pitzalis et al. (2002) conducted an observational in Unexplained syncope (n=318). Systolic arterial pressure (SAP) reductions vs. Negative tilt test was evaluated on Number of beat-to-beat SAP reductions during the first 15 minutes of tilt (p=<0.01). More than 14 systolic arterial pressure reductions during the first 15 minutes of tilt predicted a positive tilt test with 80% sensitivity and 85% specificity in a prospective validation cohort.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: