Key result
Tenecteplase versus alteplase before thrombectomy reveals a reciprocal link between early reperfusion and first-pass effect.
Why the study?
The study was conducted to investigate the interplay of early reperfusion and first-pass effect in patients receiving thrombolysis with tenecteplase versus alteplase prior to endovascular treatment.
Does tenecteplase compared to alteplase affect early reperfusion and first-pass effect in stroke patients prior to endovascular treatment?
Does tenecteplase compared to alteplase affect early reperfusion and first-pass effect in stroke patients prior to endovascular treatment?
This study investigates the relationship between early reperfusion and first-pass effect in stroke patients receiving tenecteplase versus alteplase before thrombectomy.
To investigate the interplay of early reperfusion (ER) and first-pass effect (FPE) between patients receiving thrombolysis with tenecteplase (TNK) and alteplase (TPA) prior to endovascular treatment (EVT).
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Kline et al. (2026) studied this question. Tenecteplase compared with alteplase prior to stroke thrombectomy demonstrates a reciprocal relationship between early reperfusion and the first-pass effect.
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