Combined aerobic and resistance training significantly improved 6-minute walk distance (466.39 vs 440.12 m, p=0.013) and 5-sit-to-stand time compared to aerobic training alone post-valve surgery.
RCT (n=89)
Does early phase 2 cardiac rehabilitation with combined aerobic and resistance training improve functional outcomes in patients post-open heart valve surgery compared to aerobic training alone?
Combined aerobic and resistance training in early phase 2 cardiac rehabilitation significantly improves functional capacity compared to aerobic training alone in patients recovering from heart valve surgery.
Absolute Event Rate: 466.39% vs 440.12%
p-value: p=0.013
Abstract Background Cardiac rehabilitation integrating aerobic and resistance training has demonstrated efficacy in enhancing short-term functional capacity in patients following valve surgery. Combined aerobic and resistance exercises targeting upper and lower extremities are considered safe and effective in improving exercise capacity, muscle strength, and quality of life in patients post-heart valve surgery. Aim This study aimed to evaluate the impact of early phase 2 cardiac rehabilitation with combined aerobic and resistance training compared to aerobic training alone on functional outcomes in patients post-open heart valve surgery. Methods In a prospective randomized controlled trial, 89 patients (2 weeks to 1 month post-surgery) were assigned to either an intervention group (n=46, supervised combined aerobic and resistance training for 4 weeks, 12 sessions) or a control group (n=43, aerobic training alone). Primary endpoints included the Six-Minute Walk Test (6MWT), Five Sit-to-Stand Test (5STS), handgrip strength, and quality of life assessed by the Kansas City Cardiomyopathy Questionnaire (KCCQ). Statistical analyses included descriptive statistics, independent t-tests, and paired t-tests. Results At baseline, no significant differences were observed between the intervention and control groups for 6MWT (p = 0.153) or 5STS (p = 0.683). At post-intervention, the intervention group exhibited significantly better performance in the 6MWT (466.39 ± 54.02 vs. 440.12 ± 41.95 m, p = 0.013) and 5STS (7.56 ± 1.38 vs. 9.20 ± 1.83 s, p 0.001). Paired t-tests revealed significant improvements in both groups (p 0.001), with greater gains in the intervention group (6MWT: +87.91 m vs. +78.95 m; 5STS: 3.42 s vs. 2.00 s). There were no significant between-group differences in post-intervention handgrip strength (p = 0.179) or in the average quality-of-life score measured using the KCCQ (p = 0.375). Conclusion Early phase 2 cardiac rehabilitation with combined aerobic and resistance training significantly enhances functional capacity (6MWT, 5STS)compared to aerobic training alone in patients post-heart valve surgery. These findings support the safety and efficacy of combined exercise regimens in improving physical function.
Siagian et al. (Mon,) conducted a rct in post-open heart valve surgery (n=89). Combined aerobic and resistance training vs. Aerobic training alone was evaluated on Six-Minute Walk Test (6MWT) (p=0.013). Combined aerobic and resistance training significantly improved 6-minute walk distance (466.39 vs 440.12 m, p=0.013) and 5-sit-to-stand time compared to aerobic training alone post-valve surgery.
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