Key result
The overall recurrence rate of cardiac neonatal lupus in subsequent pregnancies among mothers with anti-SSA/Ro antibodies was 17.4% (95% CI 11.1-23.6%).
Why the study?
What is the recurrence rate of cardiac neonatal lupus in subsequent pregnancies among mothers with anti-SSA/Ro antibodies?
Population
161 pregnancies of 129 mothers with anti-SSA/Ro antibodies who previously had a child with cardiac neonatal…
Design
Cohort
Authors
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Informs counseling after cardiac neonatal lupus; leaves open whether maternal factors or interventions modify recurrence risk.
Cohort (n=129)
What is the recurrence rate of cardiac neonatal lupus in subsequent pregnancies among mothers with anti-SSA/Ro antibodies?
The recurrence rate of cardiac neonatal lupus in subsequent pregnancies is approximately 17% and is not predicted by maternal clinical factors or steroid use.
Llanos et al. (2009) conducted a cohort in Cardiac neonatal lupus (n=129). Maternal and fetal risk factors was evaluated on Recurrence of cardiac neonatal lupus in a subsequent pregnancy (95% CI 11.1-23.6). The overall recurrence rate of cardiac neonatal lupus in subsequent pregnancies among mothers with anti-SSA/Ro antibodies was 17.4% (95% CI 11.1-23.6%).
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