Key result
Follicular phase linked to ~29% lower resting LF power versus the luteal phase.
Why the study?
Existing literature regarding the effect of menstrual phases on cardiovascular and autonomic regulation during central hypovolemia was contradictory.
Does the menstrual cycle phase influence hemodynamic and autonomic responses to central hypovolemia in healthy young females?
Population
14 healthy young females (8 follicular phase, 6 luteal phase)
Comparison
Follicular phase vs luteal phase during resting and LBNP-induced central hypovolemia
Design
Companion physiological study
Authors
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Menstrual phase may influence resting autonomic balance in females; hypothesis-generating and should not yet change clinical HRV interpretation.
Observational (n=14)
No
Does the menstrual cycle phase influence hemodynamic and autonomic responses to central hypovolemia in healthy young females?
Absolute Event Rate: 41.38% vs 58.47%
p-value: p=0.01
The menstrual phase significantly influences resting autonomic tone and cardiovascular reactivity to central hypovolemia, with higher sympathetic activity and better tolerance observed during the luteal phase.
Shankhwar et al. (2024) conducted an observational in Healthy (n=14). Follicular phase vs. Luteal phase was evaluated on Resting low-frequency (LF) band power (p=0.01). Females in the follicular phase showed significantly lower resting values of low-frequency band power (41.38 vs 58.47 n.u., p=0.01) and higher high-frequency band power compared to those in the luteal phase.
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