What question did this study set out to answer?

This study aimed to evaluate the prevalence of objective Sjögren’s disease signs in Ro52-positive patients with idiopathic inflammatory myopathies.

June 13, 2026Frontiers in ImmunologyOpen Access

Antibodies against Ro52 in idiopathic inflammatory myopathies are associated with objective sicca symptoms

View Full Paper

Ask AI

Bookmark

This study aimed to evaluate the prevalence of objective Sjögren’s disease signs in Ro52-positive patients with idiopathic inflammatory myopathies.
Retrospective data analysis of patients from Hannover Medical School between 2018 and 2024.
Included 97 patients diagnosed with idiopathic inflammatory myopathy.
Determined anti-Ro52 antibodies using myositis immunoblot and evaluated associations with ILD and sicca symptoms.
Anti-Ro52 antibodies detected in 46 of 97 patients (47%).
Anti-Ro52 antibodies associated with ILD (OR 3.5; p = 0.004).
Anti-Ro52 antibodies correlated with reduced saliva and tear production (OR 6.3; p=0.026).

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Retrospective data analysis reveals connections between anti-Ro52 antibodies, objective sicca symptoms, and ILD in myopathy patients, suggesting clinical implications.

Cite This Study

Meinecke et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf2a9faef96ed7f05562d https://doi.org/10.3389/fimmu.2026.1841969

View Full Paper

Ask AI

Bookmark

Implication

Retrospective data analysis reveals connections between anti-Ro52 antibodies, objective sicca symptoms, and ILD in myopathy patients, suggesting clinical implications.

Antibodies against Ro52 in idiopathic inflammatory myopathies are associated with objective sicca symptoms

Key Points

Discussion

Implication

Cite This Study

Antibodies against Ro52 in idiopathic inflammatory myopathies are associated with objective sicca symptoms

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider