A Leg Predominant Presentation of LGI1 Encephalitis with Co-existing P/Q-type Calcium Channel Antibody (P2-1.010)

Q: What does this research mean for the field?

LGI1 encephalitis can present with leg-predominant hyperkinetic movement attacks and co-existing P/Q-type calcium channel antibodies. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Malika Faouzi; Alexandra Galati; Suman Kaza; Michiko Bruno

doi:10.1212/wnl.0000000000217745

June 9, 2026Neurology

A Leg Predominant Presentation of LGI1 Encephalitis with Co-existing P/Q-type Calcium Channel Antibody (P2-1.010)

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Key Points

The aim is to describe the manifestation of LGI1 encephalitis with a focus on leg predominant symptoms.
In-depth clinical case description of the patient.
Observation of movement patterns and attacks.
Assessment of antibody presence.
The patient exhibited leg predominant hyperkinetic movement attacks.
Presence of P/Q-type calcium channel antibodies was confirmed.

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Implication

Case report describes leg predominant hyperkinetic movement attacks in LGI1 encephalitis, suggesting complex interactions.

Abstract

To describe a case of LGI1 encephalitis presenting with leg predominant hyperkinetic movement attacks.

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Cite This Study

Faouzi et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf300faef96ed7f0558e9 https://doi.org/10.1212/wnl.0000000000217745

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A Leg Predominant Presentation of LGI1 Encephalitis with Co-existing P/Q-type Calcium Channel Antibody (P2-1.010)

Key Points

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Implication

Abstract

Discussion

Cite This Study

A Leg Predominant Presentation of LGI1 Encephalitis with Co-existing P/Q-type Calcium Channel Antibody (P2-1.010)

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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