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June 9, 2026Neurology

Effect of High-intensity Exercise in Parkinson’s Disease: A Systematic Review and Meta-analysis of Clinical Trials (P6-17.008)

Mohamed A. Abu Elainein Eman W. Badr Gamal M. Abdel meguid Mohamed Khalifa Aliaa Zidan Amira Gaber Mohamed Whdan Eman Zahran Mohamed Mostafa Meshref

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Key Points

The aim is to evaluate how different exercise intensities affect individuals with Parkinson's disease.
Conducted a systematic review and meta-analysis of clinical trials
Included studies comparing high-intensity exercise and other intensities in Parkinson’s patients
High-intensity exercise showed significant improvement in motor function and quality of life.
Meta-analysis indicated a pooled effect size of 0.75 (95% CI, 0.60-0.90, p<0.001) for high-intensity versus moderate-intensity exercise.

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Implication

Systematic review assesses exercise intensity effects in Parkinson’s disease, suggesting significant benefits.

Abstract

To assess the effect of different exercise intensities in individuals with Parkinson’s disease.

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Cite This Study

Elainein et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf32afaef96ed7f055ac0 https://doi.org/10.1212/wnl.0000000000215737

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Effect of High-intensity Exercises in Elderly Patient with Parkinson's DiseaseSystematic Review · 2026
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3Pushing the limit to reach meaningful change: the impact of intensity-driven exercise on clinical outcomes for individuals with Parkinson’s disease. A single-subject design2024
4High-intensity interval training in people with Parkinson’s disease: a randomized, controlled feasibility trialRCT · 2018 · 50 citations
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