Efficacy and Safety of Direct Oral Anticoagulants vs Warfarin for Cerebral Venous Thrombosis: An Updated Systematic Review and Meta-analysis (P3-5.010)

June 9, 2026Neurology

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Key Points

This research aims to assess the safety and efficacy of direct oral anticoagulants compared to warfarin for cerebral venous thrombosis.
Conducted a systematic review and meta-analysis of existing studies comparing DOACs and warfarin.
Included various studies evaluating treatment outcomes for CVT using DOACs or warfarin.
DOACs demonstrated comparable efficacy to warfarin for treating CVT with a lower incidence of major bleeding events.
Findings suggest that DOACs are potentially safer, making them a viable alternative to warfarin for CVT treatment.

Systematic review compares safety and efficacy of DOACs and warfarin for treating CVT, indicating treatment preferences.

To compare the safety and efficacy of direct oral anticoagulants (DOACs) versus warfarin for the treatment of Cerebral Venous Thrombosis (CVT).

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Vedula et al. (2026) studied this question.

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