Direct Oral Anticoagulants versus Vitamin K Antagonists in Cerebral Venous Thrombosis: A Systematic Review and Meta-analysis (P7-4.010)

Zain ul Abideen; Hassan Waseem; Areeba Shoaib; Nohela Rehman; Muhammad Osama; Barka Sajid; Muhammad Mukhlis; Muhammad Ansari; Muhammad Ansari; Rowaid Ahmad; Justin Chih-Yao Chen; Jamir Pitton Rissardo; Ana Leticia Fornari Caprara; Vishnu Byroju; Adam Dmytriw; Brandon Lucke-Wold

doi:10.1212/wnl.0000000000212992

June 9, 2026Neurology

Direct Oral Anticoagulants versus Vitamin K Antagonists in Cerebral Venous Thrombosis: A Systematic Review and Meta-analysis (P7-4.010)

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Key Points

This meta-analysis compares the effectiveness and safety of direct oral anticoagulants and vitamin K antagonists in treating cerebral venous thrombosis.
Conducted a systematic review and meta-analysis of available studies on DOACs and VKAs for CVT.
Analyzed effectiveness and safety outcomes from included studies.
Evaluated multiple databases for relevant literature.
Found that DOACs had significant effectiveness in treating CVT compared to VKAs.
Safety profiles of DOACs were either superior or comparable to VKAs in the analyzed studies.

Implication

Systematic review and meta-analysis compares anticoagulant therapies for cerebral venous thrombosis, highlighting effectiveness and safety.

Abstract

This meta-analysis aims to compare the effectiveness and safety of direct oral anticoagulants (DOACs) with those of vitamin K antagonists (VKAs) in treating cerebral venous thrombosis (CVT).

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Cite This Study

Abideen et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf393faef96ed7f0560d9 https://doi.org/10.1212/wnl.0000000000212992

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Direct Oral Anticoagulants versus Vitamin K Antagonists in Cerebral Venous Thrombosis: A Systematic Review and Meta-analysis (P7-4.010)

Key Points

Implication

Abstract

Discussion

Cite This Study

Direct Oral Anticoagulants versus Vitamin K Antagonists in Cerebral Venous Thrombosis: A Systematic Review and Meta-analysis (P7-4.010)

Key Points

Implication

Abstract

Discussion

Cite This Study

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