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June 9, 2026Neurology

Linking Juxtacortical Perivascular Spaces to Cerebral Amyloid Angiopathy: A 5.0T MRI Investigation (P9-13.004)

Y Zhou Lixin Zhou Yi-Cheng Zhu Jun Ni

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Key Points

This research aims to determine how the burden of juxtacortical perivascular spaces relates to cerebral amyloid angiopathy using advanced MRI technology.
In-vivo imaging using 5.0T MRI to assess juxtacortical perivascular spaces.
Analysis of the relationship between jPVS burden and cerebral amyloid angiopathy.
Increased jPVS burden correlates with higher prevalence of cerebral amyloid angiopathy on imaging.
The study identifies potential diagnostic indicators for monitoring CAA progression.

Implication

Investigation links jPVS burden to cerebral amyloid angiopathy in vivo using 5.0T MRI, suggesting diagnostic potential.

Abstract

To explore the diagnostic relevance of in-vivo juxtacortical perivascular spaces (jPVS) burden with cerebral amyloid angiopathy (CAA) on 5.0T MRI.

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Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf393faef96ed7f0560fc https://doi.org/10.1212/wnl.0000000000216835

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Linking juxtacortical perivascular spaces to cerebral amyloid angiopathy: A study based on 5.0 T MRIOriginal Research · 2026 · 2 citations
2Perivascular Space Progression in Patients with Cerebral Amyloid AngiopathyOriginal Research · 2026
3CAA-related enlarged perivascular spaces are associated with abnormal angioarchitecture in human brain tissue: A key role for white matter atrophy?2025 · 1 citations
4Perivascular Spaces Are Associated With CSF Aβ in Cerebral Amyloid Angiopathy But Not in Deep Perforator ArteriopathyOriginal Research · 2026 · 3 citations
5Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker ProgressionCross-Sectional Study · 2026

More related papers

Visualization of perivascular spaces in Alzheimer's disease using 5.0 T MRI: A preliminary study2026
Quantification of Total White Matter Perivascular Space Volume: Follow-up in Dutch-type Cerebral Amyloid Angiopathy2025
Enlarged Centrum Semiovale Perivascular Spaces as a Noninvasive Imaging Marker of Vascular Amyloid Deposition in Amyloid-Positive Individuals without Cerebral Amyloid Angiopathy-Related Hemorrhages.2026

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