Mild Behavioral Impairment is Associated with Postmortem Alzheimer’s Disease (AD) Neuropathology (P7-13.003)

Jeremy Syrjanen; Janina Krell‐Roesch; W. Kremers; Julie Fields; Melissa Murray; Aivi Nguyen; Ross Reichard; Dennis Dickson; Darren Rothberg; Jonathan Graff-Radford; David Knopman; Ronald Petersen; Maria Vassilaki; Yonas Geda

doi:10.1212/wnl.0000000000216135

June 9, 2026Neurology

Mild Behavioral Impairment is Associated with Postmortem Alzheimer’s Disease (AD) Neuropathology (P7-13.003)

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Key Points

This research aims to investigate how mild behavioral impairment relates to neuropsychiatric symptoms and Alzheimer’s disease neuropathology postmortem.
Examined associations between mild behavioral impairment and neuropsychiatric symptoms.
Focused on postmortem neuropathology of Alzheimer’s disease and cerebrovascular issues.
Identified significant connections between mild behavioral impairment and the presence of Alzheimer’s disease neuropathology.
Highlighted associations with neuropsychiatric symptoms, implicating a potential role in Alzheimer's progression.

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Implication

Examines mild behavioral impairment's link to Alzheimer’s disease neuropathology, indicating significant associations.

Abstract

To examine the association between mild behavioral impairment (MBI), neuropsychiatric symptoms (NPS), and postmortem AD and cerebrovascular neuropathology.

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Syrjanen et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3b4faef96ed7f05622e https://doi.org/10.1212/wnl.0000000000216135

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Mild Behavioral Impairment is Associated with Postmortem Alzheimer’s Disease (AD) Neuropathology (P7-13.003)

Key Points

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Implication

Abstract

Discussion

Cite This Study

Mild Behavioral Impairment is Associated with Postmortem Alzheimer’s Disease (AD) Neuropathology (P7-13.003)

Key Points

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Implication

Abstract

Discussion

Cite This Study

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