Examines P-SYN deposition rates in idiopathic REM sleep behavior disorder, implying predictive value for disease progression.
1) Determine rates of phosphorylated alpha-synuclein (P-SYN) deposition in idiopathic REM sleep behavior disorder (iRBD) and quantify changes in P-SYN deposition over time. 2) Determine if patterns of P-SYN deposition predict phenoconversion.
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Levine et al. (2026) studied this question.
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