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June 9, 2026Neurology

Clinical Relevance of Interleukin-6 in Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease: A Systematic Review with Meta-analysis (P4-1.005)

Bryan Rudas Sulca Gerardo Luna-Peralta Alvaro Milla-Martinez Freddy Arcos Rivera Ivan Alegre-Cordero Leonardo Di Cosmo Danielle Kei Pua

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Implication

Systematic review summarizes interleukin-6 levels in cerebrospinal fluid and serum of MOGAD patients, indicating potential clinical implications.

Abstract

Objective: To summarize the current evidence on the levels of interleukin-6 (IL-6) in cerebrospinal fluid (CSF) and serum of patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).

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Cite This Study

Sulca et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf403faef96ed7f0566a2 https://doi.org/10.1212/wnl.0000000000217853

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Contributions of CSF interleukin-6 elevation to the pathogenesis of myelin oligodendrocyte glycoprotein antibody–associated disease2024 · 18 citations
2Interleukin 6 Receptor Blockade for Relapse Prevention in Myelin Oligodendrocyte Glycoprotein Antibody–Associated DiseaseCohort Study · 2026 · 4 citations
3Clinical Significance of Interleukin-6 in Multiple Sclerosis: A Systematic Review and Meta-analysis (P6-18.002)Meta-Analysis · 2026
4Evaluation of Myelin Oligodendrocyte Glycoprotein Antibodies in CSF (P7-6.001)2024
5Clinical, prognostic and pathophysiological implications of MOG-IgG detection in the CSF: the importance of intrathecal MOG-IgG synthesis2024 · 21 citations