Tailoring Plasmonic Sensitivity through Functional MXene–MOF Hybrids for High-Performance PIERS Detection of Pharmaceutical Molecules

Himanshu Yadav; Mugdha Chaturvedi; Ruchi Singh; Balla Putrakumr; Saandra Sharma; Rabindranath Lo; Soumik Siddhanta; Jayaramulu Kolleboyina

doi:10.1039/d6ta02349e

January 1, 2026Journal of Materials Chemistry A

Tailoring Plasmonic Sensitivity through Functional MXene–MOF Hybrids for High-Performance PIERS Detection of Pharmaceutical Molecules

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Key Points

This research aims to enhance the sensitivity of molecular detection using functional MXene–MOF hybrids in photo-induced enhanced Raman spectroscopy (PIERS).
Developed hybrid materials combining MXenes and metal-organic frameworks (MOFs).
Evaluated the plasmonic properties through PIERS for pharmaceutical molecules.
Achieved significant improvements in detection sensitivity compared to conventional Au/Ag substrates.
Demonstrated reduced nanoparticle aggregation and enhanced molecular confinement.

Implication

Demonstrates enhanced molecular detection with functional MXene–MOF hybrids, implying improved sensitivity for pharmaceuticals.

Abstract

Photo-induced enhanced Raman spectroscopy (PIERS) offers ultrasensitive molecular detection by exploiting localized surface plasmon resonance (LSPR). However, conventional Au/Ag PIERS substrates suffer from nanoparticle aggregation, poor molecular confinement, and limited...

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Cite This Study

Yadav et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf4aefaef96ed7f056ef9 https://doi.org/10.1039/d6ta02349e

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Tailoring Plasmonic Sensitivity through Functional MXene–MOF Hybrids for High-Performance PIERS Detection of Pharmaceutical Molecules

Key Points

Implication

Abstract

Discussion

Cite This Study

Tailoring Plasmonic Sensitivity through Functional MXene–MOF Hybrids for High-Performance PIERS Detection of Pharmaceutical Molecules

Key Points

Implication

Abstract

Discussion

Cite This Study

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